tularemia
Molecular PathogenesisContributions of TolC Orthologs to Francisella tularensis Schu S4 Multidrug Resistance, Modulation of Host Cell Responses, and VirulenceFrancisella tularensis is a Gram-negative, facultative intracellular pathogen and the causative agent of tularemia. Previous studies with the attenuated live vaccine strain (LVS) identified a role for the outer membrane protein TolC in modulation of host cell responses during infection and virulence in the mouse model of tularemia.
- Microbial Immunity and VaccinesProtective Role for Macrophages in Respiratory Francisella tularensis Infection