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Infection and Immunity
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Latest Articles

  • STAT3 Promotes Schistosome-Induced Liver Injury by Inflammation, Oxidative Stress, Proliferation, and Apoptosis Signal Pathway
    Fungal and Parasitic Infections
    STAT3 Promotes Schistosome-Induced Liver Injury by Inflammation, Oxidative Stress, Proliferation, and Apoptosis Signal Pathway

    Schistosomiasis is a parasitic helminth disease that can cause organ lesions leading to health damage. During a schistosome infection, schistosome eggs can flow into the liver along the portal vein.

    Jie Zhao, Xin Liu, Yao Chen, Lin-Shuang Zhang, Ya-Rong Zhang, Deng-Ren Ji, Shi-Meng Liu, Mo-Zhi Jia, Yong-Hong Zhu, Yong-Fen Qi, Feng-Min Lu, Yan-Rong Yu
  • Identification of <span class="named-content genus-species" id="named-content-1">Candida glabrata</span> Transcriptional Regulators That Govern Stress Resistance and Virulence
    Fungal and Parasitic Infections
    Identification of Candida glabrata Transcriptional Regulators That Govern Stress Resistance and Virulence

    The mechanisms by which Candida glabrata resists host defense peptides and caspofungin are incompletely understood. To identify transcriptional regulators that enable C. glabrata to withstand these classes of stressors, a library of 215 ...

    Elan E. Filler, Yaoping Liu, Norma V. Solis, Ling Wang, Luis F. Diaz, John E. Edwards, Scott G. Filler, Michael R. Yeaman
  • Open Access
    Genetic Variation in Toll-Like Receptor 5 and Colonization with Flagellated Bacterial Vaginosis-Associated Bacteria
    Host-Associated Microbial Communities
    Genetic Variation in Toll-Like Receptor 5 and Colonization with Flagellated Bacterial Vaginosis-Associated Bacteria

    Bacterial vaginosis (BV) is a vaginal dysbiotic condition linked to negative gynecological and reproductive sequelae. Flagellated bacteria have been identified in women with BV, including Mobiluncus spp. and BV-associated bacterium-1 (BVAB1), an uncultivated, putatively flagellated species.

    Erin J. dela Cruz, Tina L. Fiedler, Congzhou Liu, Matthew M. Munch, Christina M. Kohler, Antoinette R. Oot, Jacqueline M. Wallis, Junhui Wang, Anna Frishman, Kristina Garcia, Andrew Wiser, Jennifer E. Balkus, Sujatha Srinivasan, Jonathan L. Golob, Laura K. Sycuro, Jeanne M. Marrazzo, Thomas R. Hawn, David N. Fredricks
  • Free
    Article of Significant Interest in This Issue
    Spotlight
    Article of Significant Interest in This Issue
  • Host Response and Inflammation
    RNA sequencing reveals distinct immune responses in the chorioamniotic membranes of women with preterm labor and microbial or sterile intra-amniotic inflammation
    Kenichiro Motomura, Roberto Romero, Jose Galaz, Adi L. Tarca, Bogdan Done, Yi Xu, Yaozhu Leng, Valeria Garcia-Flores, Marcia Arenas-Hernandez, Kevin R. Theis, Meyer Gershater, Eunjung Jung, Chaur-Dong Hsu, Nardhy Gomez-Lopez
  • Bacterial Infections
    Active hexose correlated compound restores the gene expression and protein secretion of protective cytokines of immune cells in a murine stress model during Chlamydia muridarum genital infection
    Tesfaye Belay, Rajnish Sahu, Elisha Martin, Kristen Brown, Courtney Rolen, Shomonique Hankins, Brianna Punturi, Maya Patterson, Chase Chambers, Brandon Kirby, Jonathan Butchar
  • Minireview
    Molecular dynamics for antimicrobial peptide discovery
    Nicholas Palmer, Jacqueline R. M. A. Maasch, Marcelo D. T. Torres, Cesar de la Fuente-Nunez
  • Open Access
    Minireview
    Finding Order in the Chaos: Outstanding questions in Klebsiella pneumoniae pathogenesis
    Shekina Gonzalez-Ferrer, Hernán F. Peñaloza, James A. Budnick, William G. Bain, Hayley R. Nordstrom, Janet S. Lee, Daria Van Tyne
  • Minireview
    Mitochondria: powering the innate immune response to Mycobacterium tuberculosis infection
    Kristin L. Patrick, Robert O. Watson
  • Fungal and Parasitic Infections
    Purinergic P2X7 Receptor Mediates the Elimination of Trichinella spiralis by Activating NF-кb/NLRP3/IL-1β Pathway in Macrophages
    Fei Guan, Wangfang Jiang, Yang Bai, Xiao Hou, Chunjie Jiang, Chongyang Zhang, Muziazia Lupemba Jacques, Wenqi Liu, Jiahui Lei

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