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Host Response and Inflammation
Immunological responses to the relapsing fever spirochete Borrelia turicatae in infected Rhesus macaques: implications for pathogenesis and diagnosis.
Monica E. Embers, Aparna Krishnavajhala, Brittany Armstrong, Michael W. Curtis, Bapi Pahar, Hannah K. Wilder, Mike Allen, Paul Beare, Nicole R. Hasenkampf, Job E. Lopez
Bacterial Infections
Artificial selection for pathogenicity mutations in Staphylococcus aureus identifies novel factors relevant to chronic infection
Kathryn McLean, Elizabeth A. Holmes, Kelsi Penewit, Duankun K. Lee, Samantha R. Hardy, Mingxin Ren, Maxwell P. Krist, Kevin Huang, Adam Waalkes, Stephen J. Salipante
Molecular Pathogenesis
Structural and functional insights into PpgL: a metal-independent β-propeller gluconolactonase that contributes to Pseudomonas aeruginosa virulence
Ying-Jie Song, Kai-Lun Wang, Ya-Lin Shen, Jie Gao, Tao Li, Yi-Bo Zhu, Chang-Cheng Li, Li-Hui He, Qiao-Xia Zhou, Ning-Lin Zhao, Chang Zhao, Jing Yang, Qin Huang, Xing-Yu Mu, Hong Li, Deng-Feng Dou, Chuan Liu, Jian-Hua He, Bo Sun, Rui Bao
Open Access

Bacterial Infections
Spotted fever group Rickettsia infection and transmission dynamics in Amblyomma maculatum
Chanakan Suwanbongkot, Ingeborg M. Langohr, Emma K. Harris, Wellesley Dittmar, Rebecca C. Christofferson, Kevin R. Macaluso
Open Access

Host Response and Inflammation
Yersinia pestis exploit early activation of myeloid differentiation primary response 88 (MyD88) for growth in the lungs during pneumonic plague
Rachel M. Olson, Miqdad O. Dhariwala, William J. Mitchell, Deborah M. Anderson
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Peptide-Based Inhibitors of Fimbrial Biogenesis in Porphyromonas gingivalis
Sarah R. Alaei, Jin Ho Park, Stephen G. Walker, David G. Thanassi
Open Access

Bacterial Infections
Evaluating S. flexneri pathogenesis in the human enteroid model
Sridevi Ranganathan, Michele Doucet, Christen L. Grassel, BreOnna Delaine-Elias, Nicholas C. Zachos, Eileen M. Barry
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Human intestinal enteroids as a model system of Shigella pathogenesis
Benjamin J. Koestler, Cara M. Ward, C.R. Fisher, Anubama Rajan, Anthony W. Maresso, Shelley M. Payne
Microbial Immunity and Vaccines
Moderately-neutralizing epitopes in non-functional regions dominate the antibody response to Plasmodium falciparum EBA-140
Nichole D. Salinas, May M. Paing, Jagat Adhikari, Michael L. Gross, Niraj Tolia
Fungal and Parasitic Infections
Induction of Inflammatory Responses in Splenocytes by Exosomes Released from Intestinal Epithelial Cells following Cryptosporidium parvum Infection
Yang Wang, Yujuan Shen, Hua Liu, Jianhai Yin, Xin-Tian Zhang, Ai-Yu Gong, Xiqiang Chen, Siyi Chen, Nicholas W. Mathy, Jianping Cao, Xian-Ming Chen

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Infection and Immunity^® (IAI) reports key discoveries that help microbiologists, immunologists, epidemiologists, pathologists, and clinicians to gain new insights into the underlying mechanisms of host-pathogen interactions and develop novel strategies to prevent or treat infectious diseases.

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